趨化素(CHEM)單克隆抗體
Monoclonal Antibody to Chemerin (CHEM)
TIG2; RARRES2; Tazarotene-Induced Gene 2; Retinoic Acid Receptor Responder 2,Tazarotene Induced; RAR-responsive protein TIG2
- 編號UMAA945Hu22
- 物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 來源單抗制備
- 宿主小鼠
- 效價(克隆號)E10
- Ig亞型 IgG2b Kappa
- 純化方式蛋白A + 蛋白G親和純化
- 標記物無標記物
- 免疫原 RPA945Hu01-趨化素(CHEM)重組蛋白
- 緩沖液成份0.01M 磷酸鹽緩沖液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性狀液體
- 濃度1mg/mL
- 且適物種-
- 應(yīng)用WB,IHC,ICC/IF
如果抗體需用于流式細胞術(shù)，請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 302 ¥ 706 ¥ 1008 ¥ 2520 ¥ 10080
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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DAB staining on IHC-P; Samples: Human Liver Tissue; Primary Ab: 20μg/ml Mouse Anti-Human CHEM Antibody Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
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DAB staining on IHC-P;
Samples: Human Kidney Tissue;
Primary Ab: 20μg/ml Mouse Anti-Human CHEM Antibody
Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19) -
DAB staining on IHC-P;
Samples: Human Cerebrum Tissue;
Primary Ab: 20μg/ml Mouse Anti-Human CHEM Antibody
Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19) -
DAB staining on IHC-P;
Samples: Human Placenta Tissue;
Primary Ab: 20μg/ml Mouse Anti-Human CHEM Antibody
Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19) -
AF488 staining on IF;
Sample: HepG2 cell
Primary Ab: 20μg/ml Mouse Anti-Human CHEM Antibody
Second Ab: 2μg/ml AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu11)
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Figure.Western Blot;Sample: Recombinant CHEM, Human.
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通過ISO 9001、ISO 13485質(zhì)量體系認證
特異性
該抗體是針對CHEM的小鼠單克隆抗體。在免疫組織化學(xué)染色和免疫印跡實驗中能識別CHEM。
用法
Western blotting: 0.01-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
贈品
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| URPA945Hu01 | 趨化素(CHEM)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAA945Hu01 | 趨化素(CHEM)多克隆抗體 | IHC,ICC/IF |
| UFAA945Hu01 | 抗趨化素(CHEM)多克隆抗體 | FCM |
| UMAA945Hu21 | 趨化素(CHEM)單克隆抗體 | IHC,ICC/IF |
| UMAA945Hu23 | 趨化素(CHEM)單克隆抗體 | IHC,ICC/IF |
| UMAA945Hu22 | 趨化素(CHEM)單克隆抗體 | WB,IHC,ICC/IF |
| UFAA945Hu02 | 抗趨化素(CHEM)單克隆抗體 | FCM |
| ULAA945Hu54 | 趨化素(CHEM)單克隆抗體(別藻藍蛋白標記) | IHC |
| USEA945Hu | 趨化素(CHEM)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| ULMA945Hu | 趨化素(CHEM)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
| UKSA945Hu01 | 趨化素(CHEM)檢測試劑盒DIY材料(酶聯(lián)免疫吸附試驗法) | Main materials for "Do It (ELISA Kit) Yourself". |
參考文獻
| 雜志 | 參考文獻 |
| Scandinavian Journal of Gastroenterology | Serum chemerin and vaspin in non-alcoholic fatty liver disease [PubMed: 20095887] |
| Gastroenterology & Hepatology | Chemerin, vaspin and insulin resistance in chronic hepatitis C [Wiley: source] |
| Placenta | Expression and regulation of chemerin during rat pregnancy [ScienceDirect: S0143400412000902] |
| Acta Pharmacologica Sinica | Chronic ethanol consumption increases the levels of chemerin in the serum and adipose tissue of humans and rats [Nature: 201211] |
| RAED dergisi | Ankilozan spondilitli hastalarda adipositokin düzeyleri ve insülin direnci [Raeddergisi: Source] |
| Journal of Cellular and Molecular Medicine | Association of chemerin with oxidative stress, inflammation and classical adipokines in non-diabetic obese patients [Pubmed: 24702860] |
| Clinical Endocrinology | Strong correlations between circulating chemerin levels and lipoprotein subfractions in nondiabetic obese and nonobese subjects [Pubmed: 24303851] |
| Oral Dis. | Impact of OSA on Biological Markers in Morbid Obesity and Metabolic Syndrome [Pubmed:24106991] |
| Endocrine | Chemerin plays a protective role by regulating human umbilical vein endothelial cell-induced nitric oxide signaling in preeclampsia [Pubmed:24840719] |
| The Clinical Respiratory Journal | Relationship between plasma chemerin levels and disease severity in COPD patients [Pubmed:24865134] |
| Gynecol Endocrinol. | Elevated serum chemerin in Chinese women with hyperandrogenic PCOS [Pubmed:24927079] |
| Endocrine. | Protective effect of liraglutide against ER stress in the liver of high-fat diet-induced insulin-resistant rats. [Pubmed:25471281] |
| Obesity Surgery | Long-term Effect of Ileal Transposition on Adipokine Serum Level in Zucker (Orl)-Lepr fa Fatty Rats [Pubmed:25697126] |
| Dermatologica Sinica | Chemerin and calprotectin levels correlate with disease activity and inflammation markers in psoriasis vulgaris [Sciencedirect:S1027811714000470] |
| Dis Markers | Serum Chemerin Levels in relation to Osteoporosis and Bone Mineral Density: A Case-Control Study [PubMed: 26170530] |
| Med Sci Monit | Association of Serum Chemerin Levels with Acute Ischemic Stroke and Carotid Artery Atherosclerosis in a Chinese Population [PubMed: 26471865] |
| Endocrine | Protective effect of liraglutide against ER stress in the liver of high-fat diet-induced insulin-resistant rats [PubMed: 25471281] |
| Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | Effects of alpha-lipoic acid on chemerin secretion in 3T3-L1 and human adipocytes [Pubmed:26721419] |
| Medicine (Baltimore). | Association?of?chemerin?levels?and?bone?mineral?density?in?Chinese?obese?postmenopausalwomen. [pubmed:27583869] |
| Oxidative?Medicine?and?Cellular?Longevity | Changes of Plasma FABP4, CRP, Leptin, and Chemerin Levels in relation to Different Dietary Patterns and Duodenal-Jejunal Omega Switch Surgery in Sprague?… [Pubmed:29849871] |
| Current?Eye?Research | Chemerin is associated with diabetic retinopathy in type 2 diabetes [Pubmed:25848840] |
| Journal of?Oral?Rehabilitation | Expression of chemerin in the synovial fluid of patients with temporomandibular joint disorders [Pubmed:29331039] |
| International?Journal?of?Cancer | Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer [Pubmed: 30252132] |
| Experimental Gerontology | The decline of whole-body glucose metabolism in ovariectomized rats [Pubmed: 30292771] |
| Pancreatology | Chemerin alleviates acute pancreatitis in the rat thorough modulation of NF-κB signal [Doi: 10.1016/j.pan.2019.02.005] |
| Hypertens Pregnancy | Protective effect of vitamin D supplementation in a rat modal of preeclampsia: a possible implication of chemerin [Pubmed: 30922121] |
| Pancreatology | Chemerin alleviates acute pancreatitis in the rat thorough modulation of NF-kB signal [Pubmed: 30833212] |
| Digestion | Association between High Levels of Circulating Chemerin and Colorectal Adenoma in Men [Pubmed: 31269491] |
| Vitamin D Supplementation Reduces Serum Chemerin Level in Gestational Diabetes Mellitus Rat Model [] | |
| Aging Medicine | Plasma levels of adiponectin and chemerin are associated with early stage of atherosclerosis in older adults with type 2 diabetes mellitus [] |
| Eur J Nutr | The dietary inflammatory index is associated with anti-and pro-inflammatory adipokines in Brazilian schoolchildren [33575861] |
| Eur J Pediatr | Pro-and anti-inflammatory adipokines are associated with cardiometabolic risk markers in Brazilian schoolchildren [33834274] |
| Indian Journal of Forensic Medicine & Toxicology | Altered Serum Marker of Adipokines Profile in Breast Cancer Women [] |
| Int J Womens Health | Association of High Serum Chemerin with Bone Mineral Density Loss and Osteoporotic Fracture in Elderly Chinese Women [Pubmed:35140527] |
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